Araceli Buendia Ilagan, 63, came down with the illness while working in the intensive care unit at Jackson Memorial Hospital, news station WSVN reported.
The Jackson Health System, which runs the hospital, confirmed on Saturday that she “recently died from complications of COVID-19.”
Her brother, Roy Buendia, mourned her death Saturday in a Facebook post, saying she was on the front lines in the coronavirus battle.
“She was nursing those patients with [coronavirus] in their hospital and unfortunately contracted [it] and became unwell,” he wrote.
“My dearest sister, we admired you for your dedication on your profession…You’re a true ‘hero’ in this fight against Covid-19.”
Florida has seen at least 54 deaths from the virus as it spreads to more than 4,000 people in the state, according to the latest figures from Johns Hopkins University.